Common Registration Assessment, Part 1
Urine output and fluid balance calculations
Three original questions on urine output thresholds and balance charts, with the working shown and the usual traps pointed out.
Published 4 October 2026. Independent revision material, not GPhC questions, not for patient care.

Urine output is assessed in mL per kg per hour. An output below 0.5 mL/kg/h in an adult is oliguria and needs review, so the first step is always to express what you see in those units.
A fluid balance chart adds every input and every output over 24 hours. A positive balance means intake exceeded output.
The method
- Convert the measured urine volume to mL per hour using the collection period.
- Divide by the weight in kg for mL/kg/h and compare with 0.5.
- For a balance chart, total all inputs (oral, IV, feeds) and all outputs (urine, vomit, drains).
- Balance = inputs minus outputs; state whether it is positive or negative.
- Check your totals column by column before answering.
Three practice questions
Work each one on paper first, then open the answer. All drugs and patients are fictional.
Question 1
A 70 kg patient passed 510 mL of urine in 24 hours. What is the output in mL/kg/h to two decimal places, and is it below the 0.5 mL/kg/h threshold?
Show the answer
Answer: 0.30 mL/kg/h, yes, it is below the threshold
Working: 510 ÷ 24 = 21.25 mL/h. 21.25 ÷ 70 = 0.30 mL/kg/h, which is below 0.5, so the patient is oliguric.
Question 2
Over 24 hours a patient takes 1,500 mL orally and 900 mL intravenously, and passes 1,600 mL of urine, 200 mL of vomit and 150 mL from a drain. What is the fluid balance?
Show the answer
Answer: Positive 450 mL
Working: Inputs: 1,500 + 900 = 2,400 mL. Outputs: 1,600 + 200 + 150 = 1,950 mL. Balance = 2,400 - 1,950 = +450 mL.
Question 3
An 80 kg patient should produce at least 0.5 mL/kg/h. Over 8 hours they passed 260 mL. How far short are they of the minimum expected volume?
Show the answer
Answer: 60 mL short
Working: Minimum rate: 0.5 × 80 = 40 mL/h. Over 8 hours that is 320 mL. 320 - 260 = 60 mL short.
How this is examined
Always reduce urine output to mL/kg/h before judging it, and lay balance charts out as two totals before subtracting.
Where marks are lost
- Comparing the raw 24 hour volume with 0.5 without converting to mL/kg/h.
- Missing an output line on the chart, usually drains or insensible losses stated in the stem.
- Reporting the balance sign the wrong way round: positive means more in than out.
Frequently asked questions
Is 0.5 mL/kg/h the only threshold used?
It is the standard adult oliguria threshold used in these questions. Some definitions use 30 mL per hour, which gives a similar answer for average weights.
What counts as an input?
Everything the patient takes in: oral fluids, IV infusions, IV medicines given as volumes, and tube feeds. Include blood products if the stem lists them.
Sources
- NICE NG29, intravenous fluid therapy in children and young people in hospital
- GPhC, Common Registration Assessment specification and permitted items for 2026
The questions above are original and use fictional drugs. PreRegExamPrep is not affiliated with or endorsed by the General Pharmaceutical Council.
Practise until the method is automatic
Try 15 free questions with worked answers. No sign-up required.
More calculation topics
- Dose by weight calculations for the GPhC assessment
- Volume to give: liquid medicine calculations
- Percentage strength calculations: w/v, w/w and ratios
- Dilution calculations with C1V1 = C2V2
- Infusion rate calculations in mL per hour
- Drip rate calculations: drops per minute
- Body surface area calculations
- Creatinine clearance (Cockcroft-Gault) calculations
- Moles and millimoles calculations
- Displacement volume calculations for reconstitution
- Quantity to supply calculations
- Using a provided formula in calculations
- Dose information from packaging and labels
- Diluting a stock to a lower strength
- Medicine cost and switch calculations
- Rounding rules in calculations
- Enteral feed rate calculations
- Electrolyte content over time
- Infusion dose per kg per hour
- Rounding doses to measurable volumes
- Relative risk and relative risk reduction
- Absolute risk reduction and number needed to treat
- Odds ratio and confidence intervals
- Relative versus absolute risk reduction
- Loading dose and volume of distribution
- Top-up doses from measured drug levels
- Salt correction factors
- Mass and molar drug concentrations
- Half-life and falling drug levels
- Steady-state concentration and infusion rate
- Bioavailability and equivalent oral doses
- Oral maintenance dose and dosing interval
- Elimination rate constant and half-life
- Accumulation towards steady state
- Ratio strengths and one in X
- Serial dilution factors
- Mixing solutions of different strengths
- Tablet quantities for reducing regimens
- Equivalent doses from provided conversion tables
- Thresholds and dose-banding algorithms
- Unit conversions for mass and volume
- Units and units per mL
- Reconstituting powders and final concentration
- Millimoles and milliequivalents
- Infusion time and volume remaining
- Days supply from pack sizes
- Percentage w/v and w/w conversions
- Ideal and adjusted body weight from formulae
- Diluting creams and ointments by weight
- Scaling a formula to a batch size
- Age-band doses from a provided table
- Tablet fractions and split doses
- Stones, pounds, inches and metric conversions
- Micrograms per minute from mg per hour
- Percentage change and mark-up
- Molar solutions and mass per volume
- Osmolarity from component concentrations
- Direct proportion and cross-multiplication
- Scientific notation and very small quantities
- Stock use and reorder quantities
- Parts per million and very dilute solutions
- Sodium chloride equivalents and isotonic solutions
- Density and specific gravity conversions
- Doses per day and hours between doses
- Finding the volume of diluent to add
- Capping a dose at a stated maximum
- Whole vials and ampoules to draw up
- Reading values from a provided graph
- Micrograms per kg per minute infusions
- Percentage composition of a compound preparation
- Suppository displacement values
- Isotonicity by freezing point depression
- Energy content of parenteral nutrition
- Syringe driver rate calculations
- Area under the curve calculations
- Renal dose adjustments using provided bands
- Insulin units and infusion calculations
- Working backwards from a stated dose
- Doses and days from multi-dose devices
- Combined additives in one infusion
- BMI calculations for the GPhC assessment
- Fewest tablets to make a dose
- Clearance from half-life and volume of distribution
- Maintenance fluid requirements by weight
- Sodium load from effervescent tablets
- Ethanol content of liquid preparations
- Oxygen cylinder duration calculations
- Quantities for titration packs
- Infusion line priming and dead space
See also the formula sheet, the eight sample questions and the approved calculator page.