Rizatriptan orodispersible tablet doses and 24 hour maximums for the GPhC assessment

The manufacturer's UK product information for rizatriptan 10 mg orodispersible tablets states that the recommended dose for adults is 10 mg, that doses should be separated by at least 2 hours, and that no more than 2 doses should be taken in any 24-hour period.

The same information states that if headache returns after relief of the initial attack, one further dose may be taken within those limits, but that if a patient does not respond to the first dose, a second dose should not be taken for the same attack.

It also states that some patients should receive the lower 5 mg dose, in particular patients taking propranolol, patients with mild or moderate renal insufficiency and patients with mild to moderate hepatic insufficiency, and that rizatriptan should be separated by at least 2 hours from propranolol.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a daily maximum or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.