Common Registration Assessment, Part 1

Febuxostat 80 mg and 120 mg tablets and daily doses for the GPhC assessment

Three original practice questions, with the working shown. Read the stated prescription or plan before calculating.

Published 4 November 2026. Independent revision material, not GPhC questions, not for patient care.

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Photo from Pexels, used under the Pexels licence. It is a stock image and does not show the exercise.

The manufacturer's UK product information for Adenuric film-coated tablets states that the recommended dose for gout is 80 mg once daily, taken with or without food.

The same information states that if the serum uric acid is above 6 mg/dL (357 micromol/L) after two to four weeks, 120 mg once daily may be considered, and that the target is to keep serum uric acid below 6 mg/dL.

It also states that gout flare prophylaxis for at least six months is recommended when starting treatment.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a daily total or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.

The method

  1. Identify the stated daily dose in milligrams and the tablet strength supplied.
  2. Divide the daily dose by the tablet strength to count tablets per day.
  3. Multiply the daily tablet count by the stated number of days for a supply quantity.
  4. Keep milligrams and tablets separate; convert only when the question asks.

Three practice questions

Work each one on paper first, then open the answer. All patients and prescriptions are fictional.

Question 1

A fictional patient takes febuxostat 80 mg once daily using 80 mg tablets. How many milligrams is this over 28 days?

Show the answer

Answer: 2,240 mg

Working: 80 mg each day x 28 days = 2,240 mg in total.

Question 2

After three weeks, a fictional patient's uric acid remains above target, so the dose is increased to febuxostat 120 mg once daily using 120 mg tablets. How many tablets are needed for a 30-day supply?

Show the answer

Answer: 30 tablets

Working: One 120 mg tablet each day x 30 days = 30 tablets.

Question 3

A fictional patient's febuxostat dose is increased from 80 mg once daily to 120 mg once daily. By how many milligrams has the daily dose increased?

Show the answer

Answer: 40 mg

Working: 120 mg - 80 mg = 40 mg more each day.

eMC SmPC: Adenuric 80 mg film-coated tablets

https://www.medicines.org.uk/emc/product/487/smpc

Where marks are lost

  • Mixing up the 80 mg starting dose and the 120 mg dose considered after two to four weeks above target.
  • Reporting the new daily dose when the question asks for the increase.
  • Multiplying tablets by days without first checking that there is one tablet each day.

Frequently asked questions

Are these official assessment questions?

No. They are original revision exercises, not official GPhC questions and not for patient care.

Does a uric acid target change the tablet arithmetic?

No. It explains why a dose may be considered. Use the exact dose and duration stated in the question.

How should I check the answer?

Check the requested unit, then work backwards from the quantity to the stated dose and duration.

Sources

The questions above are original and use fictional patients and prescriptions. PreRegExamPrep is not affiliated with or endorsed by the General Pharmaceutical Council.

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More calculation topics

See also the formula sheet, the eight sample questions and the approved calculator page.