Common Registration Assessment, Part 1

Quetiapine tablet strengths and titration days for the GPhC assessment

Three original practice questions, with the working shown. Read the stated prescription or plan before calculating.

Published 22 October 2026. Independent revision material, not GPhC questions, not for patient care.

Close-up shot of medicines on white surface
Photo from Pexels, used under the Pexels licence. It is a stock image and does not show the exercise.

The BNF lists immediate-release quetiapine tablets in seven strengths: 25 mg, 50 mg, 100 mg, 150 mg, 200 mg, 300 mg and 400 mg.

The BNF gives the usual adult start for schizophrenia as 25 mg twice a day on day 1, 50 mg twice a day on day 2, 100 mg twice a day on day 3 and 150 mg twice a day on day 4, then adjusted to a usual 300 mg to 450 mg a day in two divided doses.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and keep each day's dose separate from a running total. All prescriptions and patients here are fictional; these are revision materials, not for patient care.

The method

  1. Identify the exact strength, dose and day supplied in the question.
  2. Calculate one dose first; divide prescribed mg by mg per tablet.
  3. Apply the twice-daily frequency within each day.
  4. Add day totals only when a multi-day total is requested.
  5. Check the tablet count is a whole number before reporting it.

Three practice questions

Work each one on paper first, then open the answer. All patients and prescriptions are fictional.

Question 1

A fictional plan starts quetiapine at 25 mg twice a day on day 1 using 25 mg tablets. How many tablets is day 1?

Show the answer

Answer: 2 tablets

Working: 25 ÷ 25 = 1 tablet per dose. Twice a day is 2 tablets on day 1.

Question 2

A fictional titration uses 25 mg twice a day on day 1, 50 mg twice a day on day 2, 100 mg twice a day on day 3 and 150 mg twice a day on day 4, each day using tablets of the stated strength. How many tablets do the 4 days use in total?

Show the answer

Answer: 8 tablets

Working: Each day is 2 doses of 1 tablet: day 1 is 2 × 25 mg, day 2 is 2 × 50 mg, day 3 is 2 × 100 mg, day 4 is 2 × 150 mg. 2 + 2 + 2 + 2 = 8 tablets.

Question 3

After titration, a fictional plan settles at quetiapine 300 mg a day in two divided doses using 150 mg tablets for 30 days. How many tablets is the month?

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Answer: 60 tablets

Working: 300 ÷ 2 = 150 mg per dose, so 150 ÷ 150 = 1 tablet per dose. Two doses a day is 2 tablets a day. 2 × 30 = 60 tablets.

Exam approach

Day-by-day titrations are small sums in sequence. Do not total until every day is settled at its own dose.

Where marks are lost

  • Mixing up the seven strengths when the strength is stated in the question.
  • Carrying day 1's dose across the whole titration.
  • Counting one dose a day when the question says twice a day or two divided doses.

Frequently asked questions

Are these official assessment questions?

No. They are original revision exercises, not official GPhC questions and not for patient care.

Do I need to memorise the titration schedule?

The exercise supplies the doses. In the assessment, read any given product information exactly as written.

How should I check the answer?

Work one day at a time, then add the day totals and check the count against the stated strengths.

Sources

The questions above are original and use fictional patients and prescriptions. PreRegExamPrep is not affiliated with or endorsed by the General Pharmaceutical Council.

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More calculation topics

See also the formula sheet, the eight sample questions and the approved calculator page.