Midazolam oromucosal pre-filled syringe doses by age band for the GPhC assessment

The manufacturer's UK product information for Buccolam (midazolam) oromucosal solution states that the standard dose for a child from 1 year to under 5 years is 5 mg, from 5 years to under 10 years is 7.5 mg, and for patients aged 10 years and above is 10 mg. For infants over 6 months to under 1 year the dose is 2.5 mg, and for infants 3 to 6 months the 2.5 mg dose applies in a hospital setting only.

The same information states that each pre-filled oral syringe contains a single fixed dose, for example 2.5 mg in 0.5 ml of solution, a concentration of 5 mg per ml, and that carers should only administer a single dose.

It also states that if the seizure has not stopped within 10 minutes after administration, emergency medical assistance must be sought, and that a second or repeat dose when seizures re-occur after an initial response should not be given without prior medical advice.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a volume or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.