Zolmitriptan 2.5mg tablets and 24 hour dose limits for the GPhC assessment

The manufacturer's UK product information for zolmitriptan 2.5 mg film-coated tablets states that the recommended dose to treat a migraine attack is 2.5 mg, that if symptoms return within 24 hours following an initial response a second dose may be taken, and that a second dose should not be taken within 2 hours of the initial dose.

The same information states that if a patient does not achieve satisfactory relief with 2.5 mg doses, subsequent attacks can be treated with 5 mg doses of zolmitriptan.

It also states that in the event of recurrent attacks the total intake in a 24 hour period should not exceed 10 mg, that not more than 2 doses should be taken in any 24 hour period, and that for patients with moderate or severe hepatic impairment a maximum dose of 5 mg in 24 hours is recommended.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a daily total or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.