Prasugrel loading and maintenance tablet doses by weight for the GPhC assessment

The manufacturer's UK product information for prasugrel 10 mg film-coated tablets states that treatment should be initiated with a single 60 mg loading dose and then continued at 10 mg once a day, and that a treatment of up to 12 months is recommended unless discontinuation is clinically indicated.

The same information states that patients weighing less than 60 kg should receive the single 60 mg loading dose and then continue at 5 mg once daily, and that the 10 mg maintenance dose is not recommended for them. It states that in patients aged 75 years or older, for whom treatment is generally not recommended, a reduced maintenance dose of 5 mg should be prescribed after the loading dose if treatment is deemed necessary.

It also states that the tablets may be administered with or without food, and that the tablet must not be crushed or broken.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a daily total or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.