Enalapril daily doses and heart failure titration weeks for the GPhC assessment

The manufacturer's UK product information for enalapril 10 mg tablets states that for hypertension the initial dose is 5 to a maximum of 20 mg, depending on the degree of hypertension and the condition of the patient, that in mild hypertension the recommended initial dose is 5 to 10 mg, and that enalapril is given once daily.

The same information states that the usual maintenance dose is 20 mg daily and that the maximum maintenance dose is 40 mg daily.

It also states that for symptomatic heart failure or asymptomatic left ventricular dysfunction the initial dose is 2.5 mg under close medical supervision, increased gradually over 2 to 4 weeks to the usual maintenance dose of 20 mg given in a single dose or two divided doses. Its titration table gives week 1 as 2.5 mg a day in a single dose on days 1 to 3, then 5 mg a day in two divided doses on days 4 to 7, week 2 as 10 mg a day, and weeks 3 and 4 as 20 mg a day, with a maximum of 40 mg daily in two divided doses.

Each question fixes the values needed for its arithmetic. Write the unit beside every step and distinguish a single dose from a daily total or a supply period. All prescriptions and patients here are fictional; these are revision materials, not for patient care.